| 1 | Michigan Great Lakes Virtual AcademyMANISTEE | 21:1 | Other | Michigan Great Lakes Virtual Academy | 3,934 |
| 2 | Highpoint Virtual Academy of MichiganMesick | 27.9:1 | Other | Highpoint Virtual Academy of Michigan | 3,455 |
| 3 | Michigan Virtual Charter AcademyHAZEL PARK | 20:1 | Other | Michigan Virtual Charter Academy | 3,199 |
| 4 | Link Learning Virtual ProgramBELDING | - | High | Berrien Springs Public Schools | 2,526 |
| 5 | Cass Technical High SchoolDETROIT | 25.2:1 | High | Detroit Public Schools Community District | 2,493 |
| 6 | Dakota High SchoolMACOMB | 20:1 | High | Chippewa Valley Schools | 2,476 |
| 7 | Northville High SchoolNORTHVILLE | 23:1 | High | Northville Public Schools | 2,441 |
| 8 | Grand Blanc Community High SchoolGRAND BLANC | 20:1 | Other | Grand Blanc Community Schools | 2,377 |
| 9 | West Ottawa High School CampusHOLLAND | 20.3:1 | High | West Ottawa Public School District | 2,187 |
| 10 | Chippewa Valley High SchoolCLINTON TWP | 21:1 | High | Chippewa Valley Schools | 2,162 |
| 11 | Novi High SchoolNOVI | 18.1:1 | Other | Novi Community School District | 2,141 |
| 12 | East Kentwood High SchoolGRAND RAPIDS | 19.7:1 | High | Kentwood Public Schools | 2,068 |
| 13 | Lighthouse Connections AcademyTROY | 25.7:1 | Other | Lighthouse Connections Academy | 2,056 |
| 14 | Lake Orion Community High SchoolLAKE ORION | 16.2:1 | High | Lake Orion Community Schools | 2,035 |
| 15 | Troy High SchoolTroy | 18.1:1 | High | Troy School District | 2,032 |
| 16 | Hudsonville High SchoolHUDSONVILLE | 25.9:1 | High | Hudsonville Public School District | 1,995 |
| 17 | Fordson High SchoolDEARBORN | 16.5:1 | High | Dearborn City School District | 1,966 |
| 18 | Howell High SchoolHOWELL | 20.7:1 | High | Howell Public Schools | 1,964 |
| 19 | Western International High SchoolDETROIT | 23.6:1 | High | Detroit Public Schools Community District | 1,959 |
| 20 | Canton High SchoolCANTON | 20:1 | Other | Plymouth-Canton Community Schools | 1,899 |
| 21 | Brighton High SchoolBRIGHTON | 18.5:1 | High | Brighton Area Schools | 1,887 |
| 22 | Adlai Stevenson High SchoolSTERLING HEIGHTS | 17.7:1 | High | Utica Community Schools | 1,881 |
| 23 | Salem High SchoolCANTON | 21:1 | Other | Plymouth-Canton Community Schools | 1,871 |
| 24 | Romeo High SchoolWASHINGTON | 19.5:1 | High | Romeo Community Schools | 1,817 |
| 25 | Plymouth High SchoolCANTON | 18.7:1 | Other | Plymouth-Canton Community Schools | 1,816 |
| 26 | Loy Norrix High SchoolKALAMAZOO | 24.8:1 | High | Kalamazoo Public Schools | 1,785 |
| 27 | Dearborn High SchoolDEARBORN | 18.7:1 | High | Dearborn City School District | 1,775 |
| 28 | Rockford High SchoolROCKFORD | 18.2:1 | High | Rockford Public Schools | 1,750 |
| 29 | Anchor Bay High SchoolIRA | 22.9:1 | High | Anchor Bay School District | 1,740 |
| 30 | Star International AcademyDEARBORN HEIGHTS | 20.3:1 | Other | Star International Academy | 1,728 |
| 31 | Grandville High SchoolGRANDVILLE | 17.2:1 | High | Grandville Public Schools | 1,719 |
| 32 | Grand Ledge High SchoolGRAND LEDGE | 20.8:1 | High | Grand Ledge Public Schools | 1,704 |
| 33 | Huron High SchoolANN ARBOR | 15:1 | High | Ann Arbor Public Schools | 1,696 |
| 34 | Rochester High SchoolROCHESTER HILLS | 22.7:1 | Other | Rochester Community School District | 1,682 |
| 35 | Pioneer High SchoolANN ARBOR | 16.2:1 | High | Ann Arbor Public Schools | 1,671 |
| 36 | Belleville High SchoolBELLEVILLE | 20.6:1 | Other | Van Buren Public Schools | 1,669 |
| 37 | Henry Ford Ii High SchoolSTERLING HEIGHTS | 19.3:1 | High | Utica Community Schools | 1,663 |
| 38 | Michigan International Prep SchoolElsie | 36:1 | Other | Michigan International Prep School | 1,657 |
| 39 | Success Virtual Learning Centers of MichiganVestaburg | 54.8:1 | High | Success Virtual Learning Centers of Michigan | 1,644 |
| 40 | Grand Haven High SchoolGRAND HAVEN | 17.3:1 | High | Grand Haven Area Public Schools | 1,630 |
| 41 | Woodhaven High SchoolFLAT ROCK | 28.1:1 | High | Woodhaven-Brownstown School District | 1,629 |
| 42 | Eisenhower High SchoolSHELBY TOWNSHIP | 18.5:1 | High | Utica Community Schools | 1,625 |
| 43 | Davison High SchoolDAVISON | - | High | Davison Community Schools | 1,623 |
| 44 | Kalamazoo Central High SchoolKALAMAZOO | 22.4:1 | High | Kalamazoo Public Schools | 1,613 |
| 45 | Hartland High SchoolHARTLAND | 19.4:1 | Other | Hartland Consolidated Schools | 1,610 |
| 46 | Michigan Connections AcademyOkemos | 21.8:1 | Other | Michigan Connections Academy | 1,589 |
| 47 | Oxford High SchoolOXFORD | 18:1 | High | Oxford Community Schools | 1,568 |
| 48 | Clarkston High SchoolCLARKSTON | 19.6:1 | Other | Clarkston Community School District | 1,552 |
| 49 | High School NorthMACOMB | 21.8:1 | High | L'Anse Creuse Public Schools | 1,545 |
| 50 | Holt Senior High SchoolHOLT | 16.1:1 | High | Holt Public Schools | 1,529 |