| 1 | Lincoln High School Des Moines | 26.7:1 | High | Des Moines Independent Comm School District | 2,364 |
| 2 | Linn-Mar High School Marion | 17.5:1 | High | Linn-Mar Comm School District | 2,229 |
| 3 | Valley High School West Des Moines | 17.9:1 | High | West Des Moines Comm School District | 2,178 |
| 4 | Roosevelt High School Des Moines | 30.1:1 | High | Des Moines Independent Comm School District | 2,051 |
| 5 | East High School Des Moines | 21.7:1 | High | Des Moines Independent Comm School District | 1,952 |
| 6 | Johnston Senior High School Johnston | 20.1:1 | High | Johnston Comm School District | 1,820 |
| 7 | Prairie High School Cedar Rapids | 18:1 | High | College Comm School District | 1,766 |
| 8 | Pleasant Valley High School Bettendorf | 17.6:1 | High | Pleasant Valley Comm School District | 1,731 |
| 9 | Southeast Polk High School Pleasant Hill | 19:1 | High | Southeast Polk Comm School District | 1,722 |
| 10 | West High School Waterloo | 17.2:1 | High | Waterloo Comm School District | 1,696 |
| 11 | Iowa City High School Iowa City | 15.2:1 | High | Iowa City Comm School District | 1,666 |
| 12 | John F Kennedy High School Cedar Rapids | 17.9:1 | High | Cedar Rapids Comm School District | 1,648 |
| 13 | Marshalltown High School Marshalltown | 15.5:1 | High | Marshalltown Comm School District | 1,629 |
| 14 | Northwest High School Waukee | — | High | Waukee Comm School District | 1,574 |
| 15 | North High School Sioux City | 21.2:1 | High | Sioux City Comm School District | 1,529 |
| 16 | West Senior High School Iowa City | 15.8:1 | High | Iowa City Comm School District | 1,514 |
| 17 | Thomas Jefferson High School Cedar Rapids | 17.9:1 | High | Cedar Rapids Comm School District | 1,501 |
| 18 | Hempstead High School Dubuque | 14.5:1 | High | Dubuque Comm School District | 1,499 |
| 19 | East High School Sioux City | 20.2:1 | High | Sioux City Comm School District | 1,495 |
| 20 | Dubuque Senior High School Dubuque | 10.6:1 | High | Dubuque Comm School District | 1,490 |
| 21 | Ankeny Centennial High School Ankeny | 16.4:1 | High | Ankeny Comm School District | 1,470 |
| 22 | Iowa Virtual Academy Guttenberg | 34.5:1 | Other | Clayton Ridge Comm School District | 1,457 |
| 23 | Ames High School Ames | 16.9:1 | High | Ames Comm School District | 1,440 |
| 24 | Bettendorf High School Bettendorf | 15.1:1 | High | Bettendorf Comm School District | 1,433 |
| 25 | North High School Des Moines | 22.1:1 | High | Des Moines Independent Comm School District | 1,428 |
| 26 | Muscatine High School Muscatine | 16.7:1 | High | Muscatine Comm School District | 1,380 |
| 27 | Ankeny High School Ankeny | 17.1:1 | High | Ankeny Comm School District | 1,375 |
| 28 | Waukee High School Waukee | 15.5:1 | High | Waukee Comm School District | 1,375 |
| 29 | Cedar Falls High School Cedar Falls | 13.9:1 | High | Cedar Falls Comm School District | 1,333 |
| 30 | Abraham Lincoln High School Council Bluffs | 16.1:1 | High | Council Bluffs Comm School District | 1,333 |
| 31 | West High School Sioux City | 15.1:1 | High | Sioux City Comm School District | 1,308 |
| 32 | West High School Davenport | 16.7:1 | High | Davenport Comm School District | 1,304 |
| 33 | Urbandale High School Urbandale | 14.8:1 | High | Urbandale Comm School District | 1,301 |
| 34 | Central High School Davenport | 16.7:1 | High | Davenport Comm School District | 1,288 |
| 35 | Liberty High School North Liberty | 15.2:1 | High | Iowa City Comm School District | 1,286 |
| 36 | Southeast Junior High School Iowa City | 15:1 | Middle | Iowa City Comm School District | 1,269 |
| 37 | North High School Davenport | 17.6:1 | High | Davenport Comm School District | 1,190 |
| 38 | George Washington High School Cedar Rapids | 16.8:1 | High | Cedar Rapids Comm School District | 1,182 |
| 39 | Indianola High School Indianola | 17.8:1 | High | Indianola Comm School District | 1,165 |
| 40 | Johnston Middle School Johnston | 18.2:1 | Other | Johnston Comm School District | 1,161 |
| 41 | Thomas Jefferson High School Council Bluffs | 19.4:1 | High | Council Bluffs Comm School District | 1,146 |
| 42 | North Middle School Sioux City | 16.5:1 | Middle | Sioux City Comm School District | 1,136 |
| 43 | Summit Middle School Johnston | 16.1:1 | Middle | Johnston Comm School District | 1,118 |
| 44 | Northwest Junior High School Coralville | 13.5:1 | Middle | Iowa City Comm School District | 1,113 |
| 45 | Spring Creek - 6th Grade Pleasant Hill | 15.7:1 | Middle | Southeast Polk Comm School District | 1,112 |
| 46 | South Middle School Waukee | 15.2:1 | Middle | Waukee Comm School District | 1,092 |
| 47 | Southeast Polk Junior High Pleasant Hill | 16.5:1 | Middle | Southeast Polk Comm School District | 1,088 |
| 48 | Eleanor Roosevelt Middle School Dubuque | 14:1 | Middle | Dubuque Comm School District | 1,081 |
| 49 | North Scott High School Eldridge | 17.1:1 | High | North Scott Comm School District | 1,081 |
| 50 | East Middle School Sioux City | 14.6:1 | Middle | Sioux City Comm School District | 1,076 |